Some references related to CRISPR and genome editing (due to copyright, we are only able to provide links to some of the references):

Barrangou, R. (2012). RNA-mediated programmable DNA cleavage. Nature Biotechnology, 30(9), 836–838. doi:doi:10.1038/nbt.2357 [ link ]

Cong, L., Ran, A. F., Cox, D., Lin., S., Barretto, R., Habib, N., et al., (2013). Multiplex genome engineering using CRISPR/Cas systems. Science, published online 3 January 2013 (10.1126/science.1231143). [ full text ] [ supplementary information ]

Deltcheva, E., Chylinski, K., Sharma, C. M., Gonzales, K., Chao, Y., Pirzada, Z. A., et al. (2011). CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature, 471(7340), 602–607. doi:10.1038/nature09886 [ full text ]

Garneau, J. E., Dupuis, M.-È., Villion, M., Romero, D. A., Barrangou, R., Boyaval, P., et al. (2010). The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature468(7320), 67–71. doi:10.1038/nature09523 [ link ]

Gasiunas, G., Barrangou, R., Horvath, P., & Siksnys, V. (2012). Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proceedings of the National Academy of Sciences of the United States of America109(39), E2579–E2586. doi:10.1073/pnas.1208507109 [ full text ]

Horvath, P., & Barrangou, R. (2010). CRISPR/Cas, the Immune System of Bacteria and Archaea. Science, 327(5962), 167–170. doi:10.1126/science.1179555 [ link ]

Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012). A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity. Science, 337(6096), 816–821. doi:10.1126/science.1225829 [ link ]

Mali, P., et al. (2013). RNA-guided human genome engineering via Cas9. Science, published online 3 January 2013 (10.1126/science.1232033). [ link ]

Sapranauskas, R., Gasiunas, G., Fremaux, C., Barrangou, R., Horvath, P., & Siksnys, V. (2011). The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli. Nucleic Acids Research, 39(21), 9275–9282. doi:10.1093/nar/gkr606 [ full text ]


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